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A Simple Method to Identify Kinases That Regulate Embryonic Stem Cell Pluripotency by High-throughput Inhibitor Screening

Embryonic stem cells (ESCs) can self-renew or differentiate into all cell types, a phenomenon known as pluripotency. Distinct pluripotent states have been described, termed "naïve" and "primed" pluripotency. The mechanisms that control naïve-primed transition are poorly understoo...

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Detalles Bibliográficos
Autores principales: Williams, Charles A. C., Gray, Nathanael S., Findlay, Greg M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607952/
https://www.ncbi.nlm.nih.gov/pubmed/28570543
http://dx.doi.org/10.3791/55515