Cargando…
IRF4 Couples Anabolic Metabolism to Th1 Cell Fate Determination
Anabolic metabolism in lymphocytes promotes plasmablast and cytotoxic T cell differentiation at the expense of self-renewal. Heightened expression and function of the transcription factor IFN regulatory factor 4 (IRF4) accompany enhanced anabolic induction and full commitment to functional different...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608100/ https://www.ncbi.nlm.nih.gov/pubmed/28944344 http://dx.doi.org/10.4049/immunohorizons.1700012 |