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IRF4 Couples Anabolic Metabolism to Th1 Cell Fate Determination

Anabolic metabolism in lymphocytes promotes plasmablast and cytotoxic T cell differentiation at the expense of self-renewal. Heightened expression and function of the transcription factor IFN regulatory factor 4 (IRF4) accompany enhanced anabolic induction and full commitment to functional different...

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Detalles Bibliográficos
Autores principales:	Kratchmarov, Radomir, Nish, Simone A., Lin, Wen-Hsuan W., Adams, William C., Chen, Yen-Hua, Yen, Bonnie, Rothman, Nyanza J., Klein, Ulf, Reiner, Steven L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608100/ https://www.ncbi.nlm.nih.gov/pubmed/28944344 http://dx.doi.org/10.4049/immunohorizons.1700012

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