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Changes in striatal activity and functional connectivity in a mouse model of Huntington's disease
Hereditary Huntington’s disease (HD) is associated with progressive motor, cognitive and psychiatric symptoms. A primary consequence of the HD mutation is the preferential loss of medium spiny projection cells with relative sparing of local interneurons in the striatum. In addition, among GABAergic...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608247/ https://www.ncbi.nlm.nih.gov/pubmed/28934250 http://dx.doi.org/10.1371/journal.pone.0184580 |