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Changes in striatal activity and functional connectivity in a mouse model of Huntington's disease

Hereditary Huntington’s disease (HD) is associated with progressive motor, cognitive and psychiatric symptoms. A primary consequence of the HD mutation is the preferential loss of medium spiny projection cells with relative sparing of local interneurons in the striatum. In addition, among GABAergic...

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Detalles Bibliográficos
Autores principales: Cabanas, Magali, Bassil, Fares, Mons, Nicole, Garret, Maurice, Cho, Yoon H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608247/
https://www.ncbi.nlm.nih.gov/pubmed/28934250
http://dx.doi.org/10.1371/journal.pone.0184580