Whole-genome single-cell copy number profiling from formalin-fixed paraffin-embedded samples

A substantial proportion of tumors consist of genotypically distinct subpopulations of cancer cells. This intra-tumor genetic heterogeneity poses a significant challenge for the implementation of precision medicine. Single-cell genomics constitutes a powerful approach to resolve complex mixtures of...

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Detalles Bibliográficos
Autores principales: Martelotto, Luciano G, Baslan, Timour, Kendall, Jude, Geyer, Felipe C, Burke, Kathleen A, Spraggon, Lee, Piscuoglio, Salvatore, Chadalavada, Kalyani, Nanjangud, Gouri, Ng, Charlotte KY, Moody, Pamela, D’Italia, Sean, Rodgers, Linda, Cox, Hilary, Paula, Arnaud da Cruz, Stepansky, Asya, Schizas, Michail, Wen, Hannah Y, King, Tari A, Norton, Larry, Weigelt, Britta, Hicks, James B, Reis-Filho, Jorge S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608257/
https://www.ncbi.nlm.nih.gov/pubmed/28165479
http://dx.doi.org/10.1038/nm.4279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608257/
https://www.ncbi.nlm.nih.gov/pubmed/28165479
http://dx.doi.org/10.1038/nm.4279

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