Novel derivative of Paeonol, Paeononlsilatie sodium, alleviates behavioral damage and hippocampal dendritic injury in Alzheimer's disease concurrent with cofilin1/phosphorylated-cofilin1 and RAC1/CDC42 alterations in rats

Alzheimer’s disease (AD) is a typical hippocampal amnesia and the most common senile dementia. Many studies suggest that cognitive impairments are more closely correlated with synaptic loss than the burden of amyloid deposits in AD progression. To date, there is no effective treatment for this disea...

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Detalles Bibliográficos
Autores principales: Han, Fei, Zhuang, Ting-Ting, Chen, Jing-Jing, Zhu, Xiu-Ling, Cai, Ya-Fei, Lu, Ya-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608314/
https://www.ncbi.nlm.nih.gov/pubmed/28934273
http://dx.doi.org/10.1371/journal.pone.0185102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608314/
https://www.ncbi.nlm.nih.gov/pubmed/28934273
http://dx.doi.org/10.1371/journal.pone.0185102

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