The histone variant macroH2A confers functional robustness to the intestinal stem cell compartment

A stem cell’s epigenome directs cell fate during development, homeostasis, and regeneration. Epigenetic dysregulation can lead to inappropriate cell fate decisions, aberrant cell function, and even cancer. The histone variant macroH2A has been shown to influence gene expression, guide cell fate, and...

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Detalles Bibliográficos
Autores principales: Cedeno, Ryan James, Nakauka-Ddamba, Angela, Yousefi, Maryam, Sterling, Stephanie, Leu, Nicolae Adrian, Li, Ning, Pehrson, John R., Lengner, Christopher Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608326/
https://www.ncbi.nlm.nih.gov/pubmed/28934364
http://dx.doi.org/10.1371/journal.pone.0185196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608326/
https://www.ncbi.nlm.nih.gov/pubmed/28934364
http://dx.doi.org/10.1371/journal.pone.0185196

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