Formyl peptide derived lipopeptides disclose differences between the receptors in mouse and men and call the pepducin concept in question

A pepducin is a lipopeptide containing a peptide sequence that is identical to one of the intracellular domains of the G-protein coupled receptor (GPCR) assumed to be the target. Neutrophils express two closely related formyl peptide receptors belonging to the family of GPCRs; FPR1 and FPR2 in human...

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Detalles Bibliográficos
Autores principales: Winther, Malene, Holdfeldt, André, Sundqvist, Martina, Rajabkhani, Zahra, Gabl, Michael, Bylund, Johan, Dahlgren, Claes, Forsman, Huamei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608352/
https://www.ncbi.nlm.nih.gov/pubmed/28934373
http://dx.doi.org/10.1371/journal.pone.0185132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608352/
https://www.ncbi.nlm.nih.gov/pubmed/28934373
http://dx.doi.org/10.1371/journal.pone.0185132

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