Identification of LAG3 high affinity aptamers by HT-SELEX and Conserved Motif Accumulation (CMA)

LAG3 receptor belongs to a family of immune-checkpoints expressed in T lymphocytes and other cells of the immune system. It plays an important role as a rheostat of the immune response. Focus on this receptor as a potential therapeutic target in cancer immunotherapy has been underscored after the su...

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Detalles Bibliográficos
Autores principales: Soldevilla, Mario Martínez, Hervas, Sandra, Villanueva, Helena, Lozano, Teresa, Rabal, Obdulia, Oyarzabal, Julen, Lasarte, Juan José, Bendandi, Maurizio, Inoges, Susana, López-Díaz de Cerio, Ascensión, Pastor, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608357/
https://www.ncbi.nlm.nih.gov/pubmed/28934318
http://dx.doi.org/10.1371/journal.pone.0185169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608357/
https://www.ncbi.nlm.nih.gov/pubmed/28934318
http://dx.doi.org/10.1371/journal.pone.0185169

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