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Identification of LAG3 high affinity aptamers by HT-SELEX and Conserved Motif Accumulation (CMA)
LAG3 receptor belongs to a family of immune-checkpoints expressed in T lymphocytes and other cells of the immune system. It plays an important role as a rheostat of the immune response. Focus on this receptor as a potential therapeutic target in cancer immunotherapy has been underscored after the su...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608357/ https://www.ncbi.nlm.nih.gov/pubmed/28934318 http://dx.doi.org/10.1371/journal.pone.0185169 |