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Notch/Her12 signalling modulates, motile/immotile cilia ratio downstream of Foxj1a in zebrafish left-right organizer

Foxj1a is necessary and sufficient to specify motile cilia. Using transcriptional studies and slow-scan two-photon live imaging capable of identifying the number of motile and immotile cilia, we now established that the final number of motile cilia depends on Notch signalling (NS). We found that des...

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Detalles Bibliográficos
Autores principales: Tavares, Barbara, Jacinto, Raquel, Sampaio, Pedro, Pestana, Sara, Pinto, Andreia, Vaz, Andreia, Roxo-Rosa, Mónica, Gardner, Rui, Lopes, Telma, Schilling, Britta, Henry, Ian, Saúde, Leonor, Lopes, Susana Santos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608511/
https://www.ncbi.nlm.nih.gov/pubmed/28875937
http://dx.doi.org/10.7554/eLife.25165