Cooperative interactions enable singular olfactory receptor expression in mouse olfactory neurons

The monogenic and monoallelic expression of only one out of >1000 mouse olfactory receptor (ORs) genes requires the formation of large heterochromatic chromatin domains that sequester the OR gene clusters. Within these domains, intergenic transcriptional enhancers evade heterochromatic silencing...

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Detalles Bibliográficos
Autores principales: Monahan, Kevin, Schieren, Ira, Cheung, Jonah, Mumbey-Wafula, Alice, Monuki, Edwin S, Lomvardas, Stavros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Genes and Chromosomes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608512/
https://www.ncbi.nlm.nih.gov/pubmed/28933695
http://dx.doi.org/10.7554/eLife.28620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608512/
https://www.ncbi.nlm.nih.gov/pubmed/28933695
http://dx.doi.org/10.7554/eLife.28620

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