Susceptibility to neurofibrillary tangles: role of the PTPRD locus and limited pleiotropy with other neuropathologies

Tauopathies, including Alzheimer’s disease (AD) and other neurodegenerative conditions, are defined by a pathological hallmark: neurofibrillary tangles (NFT). NFT accumulation is thought to be closely linked to cognitive decline in AD. Here, we perform a genome-wide association study for NFT patholo...

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Detalles Bibliográficos
Autores principales: Chibnik, Lori B, White, Charles C, Mukherjee, Shubhabrata, Raj, Towfique, Yu, Lei, Larson, Eric B., Montine, Thomas J., Keene, C. Dirk, Sonnen, Joshua, Schneider, Julie A., Crane, Paul K., Shulman, Joshua M., Bennett, David A, De Jager, Philip L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608624/
https://www.ncbi.nlm.nih.gov/pubmed/28322283
http://dx.doi.org/10.1038/mp.2017.20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608624/
https://www.ncbi.nlm.nih.gov/pubmed/28322283
http://dx.doi.org/10.1038/mp.2017.20

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