Identification of a novel, fast acting GABAergic anti-depressant

Current pharmacotherapies for depression exhibit slow onset, side effects and limited efficacy. Therefore, identification of novel fast-onset antidepressants is desirable. GLO1 is a ubiquitous cellular enzyme responsible for the detoxification of the glycolytic byproduct methylglyoxal (MG). We have...

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Detalles Bibliográficos
Autores principales: McMurray, Katherine M. J., Ramaker, Marcia J., Barkley-Levenson, Amanda M., Sidhu, Preetpal S., Elkin, Pavel, Reddy, M. Kashi, Guthrie, Margaret L., Cook, James M., Rawal, Viresh H., Arnold, Leggy A., Dulawa, Stephanie C., Palmer, Abraham A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608625/
https://www.ncbi.nlm.nih.gov/pubmed/28322281
http://dx.doi.org/10.1038/mp.2017.14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608625/
https://www.ncbi.nlm.nih.gov/pubmed/28322281
http://dx.doi.org/10.1038/mp.2017.14

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