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Maternal immune activation dysregulation of the fetal brain transcriptome and relevance to the pathophysiology of autism spectrum disorder

Maternal immune activation (MIA) via infection during pregnancy is known to increase risk for autism spectrum disorder (ASD). However, it is unclear how MIA disrupts fetal brain gene expression in ways that may explain this increased risk. Here we examine how MIA dysregulates rat fetal brain gene ex...

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Detalles Bibliográficos
Autores principales: Lombardo, M V, Moon, H M, Su, J, Palmer, T D, Courchesne, E, Pramparo, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608645/
https://www.ncbi.nlm.nih.gov/pubmed/28322282
http://dx.doi.org/10.1038/mp.2017.15