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Muscle hypertrophy in hypoxia with inflammation is controlled by bromodomain and extra-terminal domain proteins

Some of the Chronic Obstructive Pulmonary Disease (COPD) patients engaged in exercise-based muscle rehabilitation programs are unresponsive. To unravel the respective role of chronic hypoxia and pulmonary inflammation on soleus muscle hypertrophic capacities, we challenged male Wistar rats to repeat...

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Detalles Bibliográficos
Autores principales: Chabert, Clovis, Khochbin, Saadi, Rousseaux, Sophie, Furze, Rebecca, Smithers, Nicholas, Prinjha, Rab, Schlattner, Uwe, Pison, Christophe, Dubouchaud, Hervé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608715/
https://www.ncbi.nlm.nih.gov/pubmed/28935884
http://dx.doi.org/10.1038/s41598-017-12112-0