Concordant and discordant gene expression patterns in mouse strains identify best-fit animal model for human tuberculosis

Immunity in infection, inflammation and malignancy differs markedly in man and mouse. Still, we learn about human immunity in large extent from experimental mouse models. We propose a novel data integration approach which identifies concordant and discordant gene expression patterns of the immune re...

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Detalles Bibliográficos
Autores principales: Domaszewska, Teresa, Scheuermann, Lisa, Hahnke, Karin, Mollenkopf, Hans, Dorhoi, Anca, Kaufmann, Stefan H. E., Weiner, January
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608750/
https://www.ncbi.nlm.nih.gov/pubmed/28935874
http://dx.doi.org/10.1038/s41598-017-11812-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608750/
https://www.ncbi.nlm.nih.gov/pubmed/28935874
http://dx.doi.org/10.1038/s41598-017-11812-x

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