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Concordant and discordant gene expression patterns in mouse strains identify best-fit animal model for human tuberculosis
Immunity in infection, inflammation and malignancy differs markedly in man and mouse. Still, we learn about human immunity in large extent from experimental mouse models. We propose a novel data integration approach which identifies concordant and discordant gene expression patterns of the immune re...
Autores principales: | Domaszewska, Teresa, Scheuermann, Lisa, Hahnke, Karin, Mollenkopf, Hans, Dorhoi, Anca, Kaufmann, Stefan H. E., Weiner, January |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608750/ https://www.ncbi.nlm.nih.gov/pubmed/28935874 http://dx.doi.org/10.1038/s41598-017-11812-x |
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