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Stepwise Evolution Improves Identification of Diverse Peptides Binding to a Protein Target
Considerable efforts have been made to develop technologies for selection of peptidic molecules that act as substrates or binders to a protein of interest. Here we demonstrate the combination of rational peptide array library design, parallel screening and stepwise evolution, to discover novel pepti...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608804/ https://www.ncbi.nlm.nih.gov/pubmed/28935886 http://dx.doi.org/10.1038/s41598-017-12440-1 |