Rat precision-cut liver slices predict drug-induced cholestatic injury

Drug-induced cholestasis (DIC) is one of the leading manifestations of drug-induced liver injury (DILI). As the underlying mechanisms for DIC are not fully known and specific and predictive biomarkers and pre-clinical models are lacking, the occurrence of DIC is often only reported when the drug has...

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Detalles Bibliográficos
Autores principales: Starokozhko, Viktoriia, Greupink, Rick, van de Broek, Petra, Soliman, Nashwa, Ghimire, Samiksha, de Graaf, Inge A. M., Groothuis, Geny M. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
In Vitro Sysytems
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608839/
https://www.ncbi.nlm.nih.gov/pubmed/28391356
http://dx.doi.org/10.1007/s00204-017-1960-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608839/
https://www.ncbi.nlm.nih.gov/pubmed/28391356
http://dx.doi.org/10.1007/s00204-017-1960-7

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