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Ranolazine promotes muscle differentiation and reduces oxidative stress in C2C12 skeletal muscle cells

PURPOSE: The purpose of this study is to investigate Ranolazine action on skeletal muscle differentiation and mitochondrial oxidative phenomena. Ranolazine, an antianginal drug, which acts blocking the late INaL current, was shown to lower hemoglobin A1c in patients with diabetes. In the present stu...

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Detalles Bibliográficos
Autores principales: Ileana, Terruzzi, Anna, Montesano, Pamela, Senesi, Fernanda, Vacante, Stefano, Benedini, Livio, Luzi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608860/
https://www.ncbi.nlm.nih.gov/pubmed/27933435
http://dx.doi.org/10.1007/s12020-016-1181-5