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Nrf2-Keap1 pathway promotes cell proliferation and diminishes ferroptosis
Cancer cells are hallmarked by high proliferation and imbalanced redox consumption and signaling. Various oncogenic pathways such as proliferation and evading cell death converge on redox-dependent signaling processes. Nrf2 is a key regulator in these redox-dependent events and operates in cytoprote...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608917/ https://www.ncbi.nlm.nih.gov/pubmed/28805788 http://dx.doi.org/10.1038/oncsis.2017.65 |