Nrf2-Keap1 pathway promotes cell proliferation and diminishes ferroptosis

Cancer cells are hallmarked by high proliferation and imbalanced redox consumption and signaling. Various oncogenic pathways such as proliferation and evading cell death converge on redox-dependent signaling processes. Nrf2 is a key regulator in these redox-dependent events and operates in cytoprote...

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Detalles Bibliográficos
Autores principales: Fan, Z, Wirth, A-K, Chen, D, Wruck, C J, Rauh, M, Buchfelder, M, Savaskan, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608917/
https://www.ncbi.nlm.nih.gov/pubmed/28805788
http://dx.doi.org/10.1038/oncsis.2017.65

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608917/
https://www.ncbi.nlm.nih.gov/pubmed/28805788
http://dx.doi.org/10.1038/oncsis.2017.65

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