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Low dose arsenite confers resistance to UV induced apoptosis via p53-MDM2 pathway in ketatinocytes

Chronic arsenite and ultraviolet (UV) exposure are associated with skin tumor. To investigate the details by low concentrations of arsenite and UV induced carcinogenesis in skin, hTERT-immortalized human keratinocytes were used as a cellular model with exposure to low concentrations of sodium arseni...

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Detalles Bibliográficos
Autores principales: Zhou, Y, Zeng, W, Qi, M, Duan, Y, Su, J, Zhao, S, Zhong, W, Gao, M, Li, F, He, Y, Hu, X, Xu, X, Chen, X, Peng, C, Zhang, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608918/
https://www.ncbi.nlm.nih.gov/pubmed/28785074
http://dx.doi.org/10.1038/oncsis.2017.67