Lysine demethylase KDM2A inhibits TET2 to promote DNA methylation and silencing of tumor suppressor genes in breast cancer

The coupling between DNA methylation and histone modification contributes to aberrant expression of oncogenes or tumor suppressor genes that leads to tumor development. Our previous study demonstrated that lysine demethylase 2A (KDM2A) functions as an oncogene in breast cancer by promoting cancer st...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, J-Y, Luo, C-W, Lai, Y-S, Wu, C-C, Hung, W-C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608919/
https://www.ncbi.nlm.nih.gov/pubmed/28785073
http://dx.doi.org/10.1038/oncsis.2017.71

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608919/
https://www.ncbi.nlm.nih.gov/pubmed/28785073
http://dx.doi.org/10.1038/oncsis.2017.71

Ejemplares similares