Cargando…

E6/E7 oncogenes in epithelial suprabasal layers and estradiol promote cervical growth and ear regeneration

Tissue growth is a common characteristic of carcinogenesis and regeneration. Here we show that suprabasal expression of human papillomavirus (HPV)16 E6/E7 oncogenes in Tg(K6b-E6/E7) mice, similar to that observed in HPV-infected human tissue, and estradiol increased cervical epithelium growth and ea...

Descripción completa

Detalles Bibliográficos
Autores principales: García, C, Hernández-García, D, Valencia, C, Rojo-León, V, Pérez-Estrada, J-R, Werner, M, Covarrubias, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608921/
https://www.ncbi.nlm.nih.gov/pubmed/28846079
http://dx.doi.org/10.1038/oncsis.2017.73