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Growth-induced stress enhances epithelial-mesenchymal transition induced by IL-6 in clear cell renal cell carcinoma via the Akt/GSK-3β/β-catenin signaling pathway

Stromal cell populations in the tumor microenvironment (TME) play a critical role in the oncogenesis and metastasis of renal cell carcinoma. In this study, we found that there are α-smooth muscle actin positive (α-SMA (+)) cells in the stroma of clear cell renal cell carcinoma (ccRCC) tissues, and t...

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Detalles Bibliográficos
Autores principales: Chen, Q, Yang, D, Zong, H, Zhu, L, Wang, L, Wang, X, Zhu, X, Song, X, Wang, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608922/
https://www.ncbi.nlm.nih.gov/pubmed/28846080
http://dx.doi.org/10.1038/oncsis.2017.74