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Receptor Quaternary Organization Explains G Protein-Coupled Receptor Family Structure

The organization of Rhodopsin-family G protein-coupled receptors (GPCRs) at the cell surface is controversial. Support both for and against the existence of dimers has been obtained in studies of mostly individual receptors. Here, we use a large-scale comparative study to examine the stoichiometric...

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Detalles Bibliográficos
Autores principales: Felce, James H., Latty, Sarah L., Knox, Rachel G., Mattick, Susan R., Lui, Yuan, Lee, Steven F., Klenerman, David, Davis, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608970/
https://www.ncbi.nlm.nih.gov/pubmed/28903045
http://dx.doi.org/10.1016/j.celrep.2017.08.072