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Engineering Synthetic Signaling Pathways with Programmable dCas9-Based Chimeric Receptors

Synthetic receptors provide a powerful experimental tool for generation of designer cells capable of monitoring the environment, sensing specific input signals, and executing diverse custom response programs. To advance the promise of cellular engineering, we have developed a class of chimeric recep...

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Detalles Bibliográficos
Autores principales: Baeumler, Toni A., Ahmed, Ahmed Ashour, Fulga, Tudor A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608971/
https://www.ncbi.nlm.nih.gov/pubmed/28903044
http://dx.doi.org/10.1016/j.celrep.2017.08.044