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Kinetic Analysis Reveals the Identity of Aβ-Metal Complex Responsible for the Initial Aggregation of Aβ in the Synapse
[Image: see text] The mechanism of Aβ aggregation in the absence of metal ions is well established, yet the role that Zn(2+) and Cu(2+), the two most studied metal ions, released during neurotransmission, paly in promoting Aβ aggregation in the vicinity of neuronal synapses remains elusive. Here we...
Autores principales: | Branch, Thomas, Barahona, Mauricio, Dodson, Charlotte A., Ying, Liming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2017
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609119/ https://www.ncbi.nlm.nih.gov/pubmed/28621929 http://dx.doi.org/10.1021/acschemneuro.7b00121 |
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