Synthesis and Evaluation of New Fluorine-18 Labeled Verapamil Analogs To Investigate the Function of P-Glycoprotein in the Blood–Brain Barrier

[Image: see text] P-glycoprotein is an efflux transporter located in the blood–brain barrier. (R)-[(11)C]Verapamil is widely used as a PET tracer to investigate its function in patients with epilepsy, Alzheimer’s disease, and other neurodegenerative diseases. Currently it is not possible to use this...

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Detalles Bibliográficos
Autores principales: Raaphorst, Renske M., Luurtsema, Gert, Schuit, Robert C., Kooijman, Esther J. M., Elsinga, Philip H., Lammertsma, Adriaan A., Windhorst, Albert D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609126/
https://www.ncbi.nlm.nih.gov/pubmed/28650628
http://dx.doi.org/10.1021/acschemneuro.7b00086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609126/
https://www.ncbi.nlm.nih.gov/pubmed/28650628
http://dx.doi.org/10.1021/acschemneuro.7b00086

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