Radioresistance of chordoma cells is associated with the ATM/ATR pathway, in which RAD51 serves as an important downstream effector

Surgery followed by radiotherapy is the standard treatment for chordomas, which are a rare but low-grade type of bone cancer arising from remnants of the embryonic notochord. However, disease recurrence following radiotherapy is common, most likely due to endogenous DNA repair mechanisms that promot...

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Detalles Bibliográficos
Autores principales: Zhang, Chao, Wang, Bing, Li, Lei, Li, Yawei, Li, Pengzhi, Lv, Guohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609200/
https://www.ncbi.nlm.nih.gov/pubmed/28962138
http://dx.doi.org/10.3892/etm.2017.4736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609200/
https://www.ncbi.nlm.nih.gov/pubmed/28962138
http://dx.doi.org/10.3892/etm.2017.4736

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