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Roux-en-Y gastric bypass surgery suppresses hypothalamic PTP1B protein level and alleviates leptin resistance in obese rats

The present study aimed to explore the effect of Roux-en-Y gastric bypass (RYGB) surgery on protein tyrosine phosphatase 1B (PTP1B) expression levels and leptin activity in hypothalami of obese rats. Obese rats induced by a high-fat diet (HFD) that underwent RYGB (n=11) or sham operation (SO, n=9),...

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Detalles Bibliográficos
Autores principales: Liu, Jia-Yu, Mu, Song, Zhang, Shu-Ping, Guo, Wei, Li, Qi-Fu, Xiao, Xiao-Qiu, Zhang, Jun, Wang, Zhi-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609316/
https://www.ncbi.nlm.nih.gov/pubmed/28947917
http://dx.doi.org/10.3892/etm.2017.4801