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Roux-en-Y gastric bypass surgery suppresses hypothalamic PTP1B protein level and alleviates leptin resistance in obese rats
The present study aimed to explore the effect of Roux-en-Y gastric bypass (RYGB) surgery on protein tyrosine phosphatase 1B (PTP1B) expression levels and leptin activity in hypothalami of obese rats. Obese rats induced by a high-fat diet (HFD) that underwent RYGB (n=11) or sham operation (SO, n=9),...
Autores principales: | Liu, Jia-Yu, Mu, Song, Zhang, Shu-Ping, Guo, Wei, Li, Qi-Fu, Xiao, Xiao-Qiu, Zhang, Jun, Wang, Zhi-Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609316/ https://www.ncbi.nlm.nih.gov/pubmed/28947917 http://dx.doi.org/10.3892/etm.2017.4801 |
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