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Analysis of drug binding pockets and repurposing opportunities for twelve essential enzymes of ESKAPE pathogens

BACKGROUND: The rapid increase in antibiotic resistance by various bacterial pathogens underlies the significance of developing new therapies and exploring different drug targets. A fraction of bacterial pathogens abbreviated as ESKAPE by the European Center for Disease Prevention and Control have b...

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Detalles Bibliográficos
Autores principales: Naz, Sadia, Ngo, Tony, Farooq, Umar, Abagyan, Ruben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609521/
https://www.ncbi.nlm.nih.gov/pubmed/28948099
http://dx.doi.org/10.7717/peerj.3765