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Elucidation of antimicrobial activity and mechanism of action by N-substituted carbazole derivatives
Compounds belonging to a carbazole series have been identified as potent fungal plasma membrane proton adenosine triphophatase (H(+)-ATPase) inhibitors with a broad spectrum of antifungal activity. The carbazole compounds inhibit the adenosine triphosphate (ATP) hydrolysis activity of the essential...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609566/ https://www.ncbi.nlm.nih.gov/pubmed/28893470 http://dx.doi.org/10.1016/j.bmcl.2017.08.067 |