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Elucidation of antimicrobial activity and mechanism of action by N-substituted carbazole derivatives

Compounds belonging to a carbazole series have been identified as potent fungal plasma membrane proton adenosine triphophatase (H(+)-ATPase) inhibitors with a broad spectrum of antifungal activity. The carbazole compounds inhibit the adenosine triphosphate (ATP) hydrolysis activity of the essential...

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Detalles Bibliográficos
Autores principales:	Clausen, Johannes D., Kjellerup, Lasse, Cohrt, Karen O'Hanlon, Hansen, John Bondo, Dalby-Brown, William, Winther, Anne-Marie L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science Ltd 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609566/ https://www.ncbi.nlm.nih.gov/pubmed/28893470 http://dx.doi.org/10.1016/j.bmcl.2017.08.067

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