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HIV exposed seronegative (HESN) compared to HIV infected individuals have higher frequencies of telomeric Killer Immunoglobulin-like Receptor (KIR) B motifs; Contribution of KIR B motif encoded genes to NK cell responsiveness

Previously, we showed that Killer Immunoglobulin-like Receptor (KIR)3DS1 homozygotes (hmz) are more frequent in HIV exposed seronegative (HESN) than in recently HIV infected (HIV+) individuals. KIR3DS1 encodes an activating Natural Killer (NK) cell receptor (NKR). The link between KIR genotype and H...

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Detalles Bibliográficos
Autores principales: Jackson, Elise, Zhang, Cindy Xinyu, Kiani, Zahra, Lisovsky, Irene, Tallon, Benjamin, Del Corpo, Alexa, Gilbert, Louise, Bruneau, Julie, Thomas, Réjean, Côté, Pierre, Trottier, Benoit, LeBlanc, Roger, Rouleau, Danielle, Tremblay, Cécile, Tsoukas, Christos M., Routy, Jean-Pierre, Ni, Xiaoyan, Mabanga, Tsoarello, Bernard, Nicole F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609756/
https://www.ncbi.nlm.nih.gov/pubmed/28938026
http://dx.doi.org/10.1371/journal.pone.0185160