VCA nanobodies target N-WASp to reduce invadopodium formation and functioning

Invasive cancer cells develop small actin-based protrusions called invadopodia, which perform a primordial role in metastasis and extracellular matrix remodelling. Neural Wiskott-Aldrich syndrome protein (N-WASp) is a scaffold protein which can directly bind to actin monomers and Arp2/3 and is a cru...

Descripción completa

Detalles Bibliográficos
Autores principales: Hebbrecht, Tim, Van Audenhove, Isabel, Zwaenepoel, Olivier, Verhelle, Adriaan, Gettemans, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609757/
https://www.ncbi.nlm.nih.gov/pubmed/28938008
http://dx.doi.org/10.1371/journal.pone.0185076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609757/
https://www.ncbi.nlm.nih.gov/pubmed/28938008
http://dx.doi.org/10.1371/journal.pone.0185076

Ejemplares similares