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DNMT3a methylation in neuropathic pain

BACKGROUND: Mu opioid receptor (MOR) plays a crucial role in mediating analgesic effects of opioids and is closely associated with the pathologies of neuropathic pain. Previous studies have reported that peripheral nerve injury downregulates MOR expression, but the epigenetic mechanisms remain unkno...

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Detalles Bibliográficos
Autores principales: Shao, Cuijie, Gao, Yong, Jin, Dan, Xu, Xin, Tan, Shuying, Yu, Hui, Zhao, Qingxiang, Zhao, Li, Wang, Wansheng, Wang, Deqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609796/
https://www.ncbi.nlm.nih.gov/pubmed/29075135
http://dx.doi.org/10.2147/JPR.S130654