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A novel deubiquitinase inhibitor b-AP15 triggers apoptosis in both androgen receptor-dependent and -independent prostate cancers

Prostate cancer (PCa) remains a leading cause of cancer-related death in men. Especially, a subset of patients will eventually progress to the metastatic castrate-resistant prostate cancer (CRPC) which is currently incurable. Deubiquitinases (DUBs) associated with the 19S proteasome regulatory parti...

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Detalles Bibliográficos
Autores principales: Cai, Jianyu, Xia, Xiaohong, Liao, Yuning, Liu, Ningning, Guo, Zhiqiang, Chen, Jinghong, Yang, Li, Long, Huidan, Yang, Qianqian, Zhang, Xiaolan, Xiao, Lu, Wang, Xuejun, Huang, Hongbiao, Liu, Jinbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609916/
https://www.ncbi.nlm.nih.gov/pubmed/28968984
http://dx.doi.org/10.18632/oncotarget.18774