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A novel deubiquitinase inhibitor b-AP15 triggers apoptosis in both androgen receptor-dependent and -independent prostate cancers
Prostate cancer (PCa) remains a leading cause of cancer-related death in men. Especially, a subset of patients will eventually progress to the metastatic castrate-resistant prostate cancer (CRPC) which is currently incurable. Deubiquitinases (DUBs) associated with the 19S proteasome regulatory parti...
Autores principales: | Cai, Jianyu, Xia, Xiaohong, Liao, Yuning, Liu, Ningning, Guo, Zhiqiang, Chen, Jinghong, Yang, Li, Long, Huidan, Yang, Qianqian, Zhang, Xiaolan, Xiao, Lu, Wang, Xuejun, Huang, Hongbiao, Liu, Jinbao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609916/ https://www.ncbi.nlm.nih.gov/pubmed/28968984 http://dx.doi.org/10.18632/oncotarget.18774 |
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