Stress inhibits tryptophan hydroxylase expression in a rat model of depression

Serotonin (5-hydroxytryptamine, 5-HT) dysfunction is associated with the pathophysiology of depression. Tryptophan hydroxylase (TPH), the rate-limiting enzyme in 5-HT biosynthesis, is believed to have essential role in many mental disorders, including depression. In the present study, we generated a...

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Detalles Bibliográficos
Autores principales: Chen, Yi, Xu, Haixia, Zhu, Mingyue, Liu, Kun, Lin, Bo, Luo, Ruxian, Chen, Chuanbai, Li, Mengsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609917/
https://www.ncbi.nlm.nih.gov/pubmed/28968985
http://dx.doi.org/10.18632/oncotarget.18780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609917/
https://www.ncbi.nlm.nih.gov/pubmed/28968985
http://dx.doi.org/10.18632/oncotarget.18780

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