Bufalin-loaded bovine serum albumin nanoparticles demonstrated improved anti-tumor activity against hepatocellular carcinoma: preparation, characterization, pharmacokinetics and tissue distribution

OBJECTIVE: To prepare and evaluate the liver-targeted drug delivery system of Bufalin with higher liver uptake and stronger antitumor activity against hepatocellular carcinoma. METHODS: Bufalin-loaded bovine serum albumin nanoparticle was prepared by desolvation method, to investigate the in vitro r...

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Detalles Bibliográficos
Autores principales: Zhang, Huiqing, Huang, Nian, Yang, Geliang, Lin, Qing, Su, Yonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609923/
https://www.ncbi.nlm.nih.gov/pubmed/28968991
http://dx.doi.org/10.18632/oncotarget.18800

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609923/
https://www.ncbi.nlm.nih.gov/pubmed/28968991
http://dx.doi.org/10.18632/oncotarget.18800

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