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Human papillomavirus 16L1-58L2 chimeric virus-like particles elicit durable neutralizing antibody responses against a broad-spectrum of human papillomavirus types

The neutralizing antibodies elicited by human papillomavirus (HPV) major capsid protein L1 virus-like particle (VLP)-based vaccines are largely type-specific. An HPV vaccine inducing cross-neutralizing antibodies broadly will be cost-effective and of great value. To this end, we constructed HPV16L1-...

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Detalles Bibliográficos
Autores principales: Chen, Xue, Liu, Hongyang, Wang, Zhirong, Wang, Shuo, Zhang, Ting, Hu, Meili, Qiao, Liang, Xu, Xuemei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609925/
https://www.ncbi.nlm.nih.gov/pubmed/28968993
http://dx.doi.org/10.18632/oncotarget.19327