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Human papillomavirus 16L1-58L2 chimeric virus-like particles elicit durable neutralizing antibody responses against a broad-spectrum of human papillomavirus types
The neutralizing antibodies elicited by human papillomavirus (HPV) major capsid protein L1 virus-like particle (VLP)-based vaccines are largely type-specific. An HPV vaccine inducing cross-neutralizing antibodies broadly will be cost-effective and of great value. To this end, we constructed HPV16L1-...
Autores principales: | Chen, Xue, Liu, Hongyang, Wang, Zhirong, Wang, Shuo, Zhang, Ting, Hu, Meili, Qiao, Liang, Xu, Xuemei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609925/ https://www.ncbi.nlm.nih.gov/pubmed/28968993 http://dx.doi.org/10.18632/oncotarget.19327 |
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