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Association of mSin1 with mTORC2 Ras and Akt reveals a crucial domain on mSin1 involved in Akt phosphorylation

mSin1 is a unique component within the mammalian target of rapamycin (mTOR) complex 2 (mTORC2), which is responsible for cellular morphology and glucose metabolism. The association between mSin1 and other mTORC2 components, as well as their functions, has been explored previously; nevertheless, the...

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Detalles Bibliográficos
Autores principales: Yao, Chien-An, Ortiz-Vega, Sara, Sun, Yun-Ya, Chien, Chiang-Ting, Chuang, Jen-Hua, Lin, Yenshou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609931/
https://www.ncbi.nlm.nih.gov/pubmed/28968999
http://dx.doi.org/10.18632/oncotarget.18818