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Dynamics of EGFR mutations in plasma recapitulates the clinical response to EGFR-TKIs in NSCLC patients

OBJECTIVES: Genomic profiling using plasma cell-free DNA (cfDNA) represents a non-invasive alternative to tumor re-biopsy, which is challenging in clinical practice. The feasibility of dynamically monitoring epidermal growth factor receptor (EGFR) mutation status using serial plasma samples from non...

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Detalles Bibliográficos
Autores principales: Xiong, Liwen, Cui, Shaohua, Ding, Jingyan, Sun, Yun, Zhang, Longfu, Zhao, Yizhuo, Gu, Aiqin, Chu, Tianqing, Wang, Huimin, Zhong, Hua, Ye, Xin, Gu, Yi, Zhang, Xin, Hu, Min, Jiang, Liyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609966/
https://www.ncbi.nlm.nih.gov/pubmed/28969034
http://dx.doi.org/10.18632/oncotarget.19139