Cargando…

Pleiotrophin promotes chemoresistance to doxorubicin in osteosarcoma by upregulating P-glycoprotein

Chemoresistance is a major hindrance to successful treatment of osteosarcoma (OS). Pleiotrophin (PTN), a neurotrophic growth factor, has been linked to the malignant characteristics of various cancer types. We retrospectively examined the correlation between PTN expression and chemoresistance in OS...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Dapeng, Liu, Liguo, Yan, Xuebing, Wang, Chunyan, Wang, Yaling, Han, Kun, Lin, Shuchen, Gan, Zhihua, Min, Daliu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609967/
https://www.ncbi.nlm.nih.gov/pubmed/28969035
http://dx.doi.org/10.18632/oncotarget.19148