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Pleiotrophin promotes chemoresistance to doxorubicin in osteosarcoma by upregulating P-glycoprotein
Chemoresistance is a major hindrance to successful treatment of osteosarcoma (OS). Pleiotrophin (PTN), a neurotrophic growth factor, has been linked to the malignant characteristics of various cancer types. We retrospectively examined the correlation between PTN expression and chemoresistance in OS...
Autores principales: | Wu, Dapeng, Liu, Liguo, Yan, Xuebing, Wang, Chunyan, Wang, Yaling, Han, Kun, Lin, Shuchen, Gan, Zhihua, Min, Daliu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609967/ https://www.ncbi.nlm.nih.gov/pubmed/28969035 http://dx.doi.org/10.18632/oncotarget.19148 |
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