Sp110 enhances macrophage resistance to Mycobacterium tuberculosis via inducing endoplasmic reticulum stress and inhibiting anti-apoptotic factors

Tuberculosis remains a leading health problem worldwide and still accounts for about 1.3 million deaths annually. Expression of the mouse Sp110 nuclear body protein (Sp110) upregulates the apoptotic pathway, which plays an essential role in enhancing host immunity to Mycobacterium tuberculosis (Mtb)...

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Detalles Bibliográficos
Autores principales: Wu, Yongyan, Guo, Zekun, Liu, Fayang, Yao, Kezhen, Gao, Mingqing, Luo, Yan, Zhang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609983/
https://www.ncbi.nlm.nih.gov/pubmed/28969051
http://dx.doi.org/10.18632/oncotarget.19300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609983/
https://www.ncbi.nlm.nih.gov/pubmed/28969051
http://dx.doi.org/10.18632/oncotarget.19300

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